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Researchers are calling for larger, well-designed randomized controlled trials in humans to determine whether these impressive animal results translate to clinical practice
What started as a glucose-lowering mechanism is now a platform for treating obesity, metabolic dysfunction-associated steatohepatitis (MASH), cardiovascular disease, and potentially neurodegenerative conditions
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After centrifugation at 1000 x g for 10 min, the supernatant (S1) was centrifuged for 20 min at 17.500 x g to yield the supernatant S2 and the pellet P2 (crude synaptosomal fraction)
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