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occasional mild digestive effects such as bloating, heartburn, or a feeling of fullness have been reported, with no major adverse events documented in clinical trials

It often causes pain, stiffness, swelling, and reduced function, especially in the shoulders, elbows, wrists, knees, or Achilles tendon

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The calculations were performed using the Turing HPC infrastructure at the CalcUA core facility of the Universiteit Antwerpen, a division of the Flemish Supercomputer Center VSC, funded by the Hercules Foundation, the Flemish Government (department EWI) and the Universiteit Antwerpen