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In this model of PD, DA-JC1, a dual GLP-1/GIP receptor agonist, improved Akt activation [138], and levels of pAkt were increased by exendin-4 and another dual GLP-1/GIP agonist, DA5-CH [131]
While this effect can be beneficial for glucose control, it raises concerns for co-administered therapies
Early weight change can also include shifts in water weight, especially if food choices change
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