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These include degrading fibrin, the fibrous protein that forms the matrix of blood clots, and its precursor fibrinogen, reducing levels of clotting factors, activating tissue plasminogen activator (tPA), and increasing concentrations of anti-clotting factors (Muric 2024

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The combination targets different pathways in the brain to help control appetite and promote weight loss

No randomized trials No controlled studies No validated imaging or outcome measures Only one very small, biased case series 2