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This is called Post-Inflammatory Hyperpigmentation (PIH)
Gastrointestinal AE with cagrisema were more than with semagutide or cagrilintide monotherapy, however the SAE and AE leading to medication discontinuation were minimal and similar between the groups [87, 90] A programme of phase 3 clinical trials (REDEFINE) assessing the safety and efficacy of cagrisema in people with obesity (NCT05567796, NCT05394519, NCT05813925) is currently ongoing
These symptoms typically emerge during dose escalation and often diminish over several weeks as physiological adaptation occurs
Following this, Lim spent some time at the University of Chicago as a fellow in a team overseen by Andrew Ivy, a leading gastroenterologist spearheading research into understanding pancreatic and gastric secretions (Davenport)
Always talk with your doctor to choose the safest and most effective option for you
