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References National Institutes of Health Office of Dietary Supplements MedlinePlus National Health Service Mayo Clinic Merck Manual This article is for general information only and is not a substitute for professional medical advice

If you have pernicious anaemia the treatment is needed for life

in Cell Metabolism , increased NAD availability stimulates PGC-1 through SIRT1 activation, leading to enhanced mitochondrial function and improved metabolic flexibility (Cant et al., Cell Metabolism )

B12 does wonders inside the body, but its benefits can also be seen on the outside as well

Here are the benefits

Increased Energy Supports ATP production, the fuel source for cells