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AICAR is itself a potent AMPK activator, the same intermediate compound that the pharmaceutical agent AICAR infusion uses to mimic exercise in rodent studies

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chinensis scavenge free radicals like reactive oxygen species (ROS), with other lignans enhancing the activity of endogenous antioxidant enzymes like superoxide dismutase (SOD) and glutathione peroxidase (GPX)

10.1155/2013/173682 192 YokoshoK.YamajiN.MaJ

In addition, the incubation the neuron cell lines with LLP-1 induced a decrease in GSH levels, mitochondrial membrane depolarization, and H 2 O 2 production rapidly

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