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doi:10.1016/j.clnesp.2020.04.010 11
Most patients see gradual weight loss over weeks to months, with measurable changes often appearing within 8 to 12 weeks during dose escalation
As noted, GLP-1 medication is generally used to manage type 2 diabetes, heart disease or weight loss, BENEOs Colindres says
Currently used antidepressant drugs, which mostly target brain monoaminergic neurotransmission, have limited clinical efficacy
Participants were randomly assigned in a 1:1:1:3 ratio to receive subcutaneous injections of tirzepatide once per week at doses of 5 mg, 10 mg, or 15 mg, or insulin glargine (100 U/mL)
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