Investigators reported it as the first Phase 3 trial in metastatic gastro-oesophageal adenocarcinoma to show median progression-free survival beyond one year and median overall survival beyond two years
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In addition, when GSH is depleted, monocyte-derived macrophages significantly increase their production of reactive oxygen species (ROS), further amplifying oxidative damage within the CNS ( Overall, GSH helps limit unwanted immune attacks in the brain
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Yes, too much heat damages glutathione, reducing its strength
10.1016/j.ijid.2020.09.324 12 BarzegariE.Ghanbari-MovahedM.ShafieiS.FarzaeiM