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Why Brand-Name Cant Match Price Structural Barriers: Public Company Obligations: Must maximize shareholder return Quarterly earnings pressure Executive compensation tied to profits Cant dramatically reduce price without stock impact Sunk Costs: Billions invested in development Need to recoup investment Justify to shareholders and board Complex Distribution System: PBMs demand rebates Wholesalers take cut Pharmacy margins Cant easily change system Market Dynamics: Limited competition (patent protection) Can charge premium prices Demand exceeds supply No pressure to reduce Eli Lilly unlikely to reduce tirzepatide prices significantly while patents protected
Theyre killing the gray market distribution channel
Reduced inflammation and improved metabolic markers
Amelioration of obesity, diabetes, and systemic inflammation with GLP-1 agonists suggests an indirect positive effect on the ocular surface
Working with a medical provider allows these factors to be evaluated carefully and safely
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