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3 Effects of L-carnitine on systemic metabolism 3.1 L-carnitine promotes fatty acid metabolism The multifaceted mechanisms by which L-carnitine modulates metabolic dysfunctionassociated steatotic liver disease are schematically summarized in Figure 1
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Triple-receptor agonist of GLP-1, GIP, and glucagon pathways
Appetite Suppression: They act on specific areas of the brain, particularly the hypothalamus, to reduce hunger signals and increase feelings of fullness or satiety
Another study also demonstrated that lactate, produced under hypoxic conditions in colorectal cancer (CRC), promotes the lactylation of H3K18, which in turn induces the transcription of autophagy enhancer protein RUBCNL, then promotes the maturation of autophagosomes, and mediates the recruitment of class III phosphatidylinositol 3-kinase(PI3K) complexes, thereby promoting tumor proliferation and mediating tumor resistance to bevacizumab [33]
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