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Combined use of both compounds is entirely unstudied in humans and carries unpredictable metabolic and cardiovascular risks

However, until regulatory bodies and robust human clinical trials catch up to the science, it remains a heavily debated therapy

Dihexa has never undergone rigorous human clinical trials establishing dosing parameters

[20] [21] Proton pump inhibitors (PPIs) such as omeprazole can reduce B12 absorption and may cause digestive upset