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B12 injections generally work faster and suit people with absorption problems or severe deficiency, while supplements are a suitable, lower-cost option for mild, diet-related shortfalls

In 2018, Bartolmas et al

Understanding MAPK signaling pathways in apoptosis

Because they take four to five half-lives often a month or more to reach steady state, blood levels and effects keep rising for weeks after a dose is fixed

Moreover, people who use enemas for this purpose risk disturbing the good bacteria in their gut, which may result in bacterial imbalances and digestive symptoms

10.3390/ijms222010914 63 NeumannP.GertzbergN.JohnsonA