As described, neuronal activity induces myelinationtherefore, it is likely that altered activity due to neuronal dysfunction may lead to changes in activity-dependent myelination (Sams, 2021)
These effects are often most prominent during dose escalation and may improve with slower titration or continued therapy
In fact, their HS flares occurred every 12 weeks while on semaglutide, compared to a flare every 8.5 weeks before starting the drug
Liraglutide (Saxenda for obesity, Victoza for diabetes) is administered as a once-daily subcutaneous injection
So it is reasonable to hypothesize that similar effects could occur in people without HIV, but that has to be confirmed in dedicated trials, he suggested
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