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In addition, BAS sevelamer suppresses the acute bile acid-induced GLP-1 secretion in patients with T2DM
The above point (2) provides evidence that loss of GLP-1 secretion with immediate pathophysiological consequences (reduced incretin effect as part of impaired postprandial beta cell function) calls for a replacement therapy with incretin-based glucose-lowering medications [3]
Furthermore, body image issues tend to be heightened during adolescence, making young people psychologically more vulnerable to weight-focused interventions
For patients receiving monthly shipments aligned with their treatment schedule, the 30-60 day stability window is plenty
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Some patients reach their target weight and choose to stay on semaglutide long-term as a maintenance medication, while others discontinue after significant loss and transition to behavioral strategies
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