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doi: 10.3389/fphar.2020.579944 Received 03 July 2020 Accepted 15 September 2020 Published 07 October 2020 Volume 11 - 2020 Edited by Leonello Fuso, Catholic University of the Sacred Heart, Italy Reviewed by Stephen C

B12 is a water-soluble vitamin that aids in metabolism, among other purposes such as red blood cell formation and nerve function

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Limited clinical data exist supporting L-carnitine's use in the management of mitochondrial dysfunction related to aging and apoptosis, AIDS-related dementia complex, drug-induced anemia, bipolar depression, cachexia, cardiovascular disease, dyslipidemia, dysthymic disorder, fatigue, drug-induced hepatotoxicity, intermittent claudication, migraine prophylaxis, muscle cramps, and drug-induced peripheral neuropathy

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