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The study was approved by the Regional Ethical Review Board in Stockholm (registration numbers EPN 2015/57931/2 and 202301601-02)

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Route of Elimination It is excreted primarily by the kidney, with about 50% excreted in one hour and over 95% within 24 hours.2 Almost none of the compound is metabolized

Subjects Sixty healthy volunteers, aged between 20 and 50 years, were eligible for this study