An intranasal spray solution of B12, also called Nascobal, with the same indications, was FDA approved in January 2005
Advantages: Oral administration, excellent safety profile, available without prescription, legal everywhere, strongest clinical evidence of any peptide for joints
Yes, the human clinical trial evidence is lacking, but there is a silver lining emerging from years of self-experimentation
As we age, our bodies can become less efficient at absorbing vitamin B12 from food, increasing the risk of deficiency
5-Amino-1MQ Summary 5-amino-1MQ is a cell-permeable analogue of methylquinolinium that has been studied for its ability to inhibit nicotinamide N-methyltransferase
Nava Mesa, B Vitamins in the nervous system: Current knowledge of the biochemical modes of action and synergies of thiamine, pyridoxine, and cobalamin, CNS Neurosci