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[5] [6] Clinical trial data from the SURPASS and SURMOUNT studies demonstrate that gastrointestinal adverse eventsincluding nausea, diarrhea, vomiting, constipation, and abdominal discomfortoccur frequently with tirzepatide

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GLP-1 receptor agonists work by increasing insulin secretion, inhibiting glucagon release, and slowing gastric emptying

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GHK-Cu also has a smaller total clinical evidence base than retinol, and L-ascorbic acid vitamin C should be kept in a separate routine step to avoid pH-driven instability

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