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Osmotic laxatives (such as polyethylene glycol or magnesium hydroxide) and stool softeners are typically lower-risk options because they work gently and don't interact directly with semaglutide's mechanism

Metabolic and bariatric surgery should be discussed with patients who have BMI 35 kg/m (regardless of comorbidities) or BMI 30-34.9 kg/m with metabolic disease, according to 2022 ASMBS/IFSO guidelines

Vitamin H stands for "haar" and "haut"

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5-HT, 5-hydroxytryptamine

Tirzepatide Tirzepatide, marketed under the names Mounjaro (for diabetes treatment) and Zepbound (for weight loss), also targets the GLP-1 RA receptor