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Conclusion: Utilizing a combination of machine learning algorithms and multi-omics techniques, we have confirmed altered proteomic and lipidomic signatures associated with PVP in MAFLD patients

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In particular, low micromolar to millimolar concentrations of Trolox are used in cell culture and in vivo applications ( Figure 5A , AX preincubation with PBS or Trolox did not significantly reduce AX-HSA adduct formation with respect to the adducts formed by the freshly prepared mixtures, whereas preincubation with TCEP showed a tendency towards decreasing adduct levels

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Identification and distribution of mRNA encoding the Y1, Y2, Y4, and Y5 receptors for peptides of the PP-fold family in the rat intestine and colon