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Another in vitro approach involves the use of primary cells isolated directly from tissue
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Alcohol- and other substance-use disorders may well benefit from the effects of GLP-1RAs on dopamine and opioid pathways that are dysregulated in addiction 243 , as seen in some of the studies we identified, and the same could also apply to other under-investigated disorders with similar underlying dysfunctions (for example, gambling disorder)
The melanocortin agonist, melanotan II, enhances proceptive sexual behaviors in the female rat
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