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In the trial-product estimand analysis (accounting for treatment adherence), reductions reached 22.7% and 2.3%, respectively, corresponding to an absolute weight loss of -21.6 kg with combination therapy

Gariepy, who has diabetes, credits the hormone with helping her to lose weight, adding she now takes only a third as much insulin as she used to need

Mol Divers 30 , 221239 (2026)

This changed after Dupr joined Roger Unger (figure 15), an American endocrinologist at the University of Texas Southwestern Medical Center in Dallas with a strong interest in glucagon and diabetes

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