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In the SUSTAIN-6 cardiovascular outcomes trial, which included 3,297 participants, semaglutide was associated with modest reductions in systolic blood pressure compared to placebo

This can lead to permanent and severe neurological issues

Clinical trials track predefined adverse events with strict reporting criteria

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It further evaluates the therapeutic potential of endogenous antioxidants, such as superoxide dismutase, catalase, and glutathione, as well as exogenous agents including vitamins A, C, E, selenium, omega-3 fatty acids, melatonin, and carnosine

The active ingredient, setmelanotide, activates melanocortin receptors in the brain, which are key to controlling hunger and metabolism