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J Endocrinol Metab
Some researchers transition from retatrutide to a lower-cost compound for maintenance purposes
Despite favorable cost-effectiveness, ICER projected affordability concerns: at current net prices of $6,830 for semaglutide and $7,973 for tirzepatide, fewer than 1% of eligible adults in the United States could be treated before surpassing ICERs budget impact threshold of $880 million annually
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Weight loss may accelerate temporarily after a dose increase
Eli Lilly is moving fast, with a 2025 submission for obesity and an aggressive early 2026 launch timeline
If that is a problem, subcutaneous syringes will need to be bought separately
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