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Conversely, suicidal thoughts, intentions, self-harm, attempts, and completed suicides are the focus of consultative psychiatry in patients prescribed GLP-1 RAs

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And this is a problem because insulin resistance will impair glutathione production via its impact on ATP production (much like magnesium deficiency)

As for alternatives, supplements containing nicotinamide riboside (NR) or nicotinamide mononucleotide (NMN) are effective NAD+ precursors

Heather Ferris told Being Patient in a LiveTalk