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The amount of estradiol produced during the menstrual cycle varies a lot in different women (see Panel A of Figure 3)

And, uh, and, uh, and that, [00:35:00] that may also be helpful

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Rigorous surveillance protocol increases detection of curable cancers associated with Barretts esophagus

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The rare individual who might consider this combination needs exceptional GI tolerance proven on prior GLP-1s, physician supervision with frequent monitoring, ability to afford $15,000-30,000 annually, understanding they're experimenting on themselves, and willingness to stop immediately if severe side effects emerge