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By targeting NNMTan enzyme highly expressed in adipose tissue and linked to insulin resistancethis compound allows researchers to explore how shifting cellular metabolism away from fat storage toward energy utilization can impact systemic health
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Cell culture studies In laboratory studies using 3T3-L1 adipocytes, a commonly used fat cell line, researchers found that 5-amino-1mq significantly reduced intracellular levels of 1-methylnicotinamide, confirming that it was successfully inhibiting NNMT
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