But other early research suggests that semaglutide and other GLP-1 medications could interact with the brains reward system in a way that helps modulate cravings, whether for food, nicotine, alcohol or other drugs
Neurobeachin ( NBEA ) Is a Novel Gene Associated with GLP 1 Receptor Agonist Associated Weight Loss. Diabetes, Obesity and Metabolism , vol
STEP1 showed ~15% mean weight loss at 68 weeks
Adjust how you eat, not just what you eat
One study found that over 90% of GLP1 users failed to meet requirements for Vitamin D, potassium and choline (Spreckley 2026)
Early Weight Loss with Liraglutide 3.0 mg Predicts 1-Year Weight Loss and is Associated with Improvements in Clinical Markers: Liraglutide 3.0 mg: Early Response, 1-Year Outcomes