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Clin Physiol Biochem (1987) 5(2):95102
This metabolic shift also impairs mitochondrial complex I function and reduces mitochondrial membrane potential (m), priming the organelle for subsequent injury ( 2+ overload through activation of the mitochondrial calcium uniporter (MCU), further depolarizing m and triggering opening of the mPTP
The choice depends on dehydration severity, blood results, vomiting duration, blood pressure, glucose, kidney and heart function, medicines, and pregnancy complications
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