By product type, the injectable GLP-1 analogues segment held the biggest market share of 70% in 2025
And when your appetite is smaller, every bite counts
Eligibility for the Medicare GLP-1 Bridge Program depends on CMS criteria
Rybelsus (Oral) : Taken daily on an empty stomach, Rybelsus must be swallowed with a small amount of water, and you should wait at least 30 minutes before eating or drinking anything else
Meanwhile, orforgliprons oral GLP-1 format may finally unlock mass adoption by removing injection-related barriers, while Survodutide, CT-388, and Pemvidutide demonstrate that dual and triple agonists, with novel combinations of GLP-1, glucagon, and GIP, can outperform monotherapies in both efficacy and metabolic breadth
The approval expands delivery formats and gives payers and prescribers an additional option that can shift demand away from pen-constrained supply