Although these agents produce substantial and sustained weight reduction, emerging clinical observations suggest that chronic therapy may be accompanied by changes in lean mass trajectory, reduced protein intake, and micronutrient insufficiency
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Lewis TD, Malik M, Britten J, San Pablo AM, Catherino WH
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1) NAD+ Nicotinamide adenine dinucleotide, also known as NAD+, NAD plus or an NAD injection, is a coenzyme involved in energy metabolism and DNA support
Vitamin B12 deficiency is particularly relevant in older patients and in anyone taking metformin concurrently, as metformin is known to reduce B12 absorption