case report aspiration anesthesia semaglutide 2023 Delayed gastric emptying: an unwanted effect of glucagon like peptide 1 agonists in the perioperative setting – The Anaesthesia Collective Semaglutide and delayed gastric emptying:

Of note, the dose of GLP-1(2836) used was selected on the basis of its dose response effect on post-IRI LVDP (Supplemental Figure 2)

Additionally, it counteracts rat hind limb ischemia by accelerating blood flow recovery and vessel number (Hsieh et al., 2017)

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GLP-1 receptor agonists slow gastric emptying, meaning food remains in the stomach and digestive tract for longer periods

Importantly, persistent HSC proliferation, combined with impaired senescence mechanisms creates a permissive microenvironment that drives fibrotic progression and even hepatocellular carcinogenesis

2022 Sep;63:101533