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During the trial design phase, digital approaches such as machine learning algorithms and digital twin models enable precise cohort selection and the generation of predictive models to optimize sample sizesan essential feature for rare diseases with limited patient pools

10.1089/ars.2011.3999 31 GarciaD.ShawR

PMID 18004285

DSIP enhances mitochondrial oxidative phosphorylation in the brain, which helps maintain brain function during periods of low oxygen (hypoxia)

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Song, J., Kang, S