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Arguably, the most clinically relevant basis for the potential of GLP-1 RAs in HF could be their effect on multiple cardiometabolic parameters that play intertwined roles across the HF-related diseases such as diabetes and obesity, which often co-exist
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The stabilization level depends heavily on whether treatment created structural dermal improvements supporting ongoing collagen synthesis or merely provided temporary stimulation requiring continuous application
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When expectations align with clinical reality, adherence improves
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