Berelowitz M, Maeda K, Harris S, Frohman LA
Mechanisms biologically plausible based on known growth factor and healing pathways
POPs are mainly excreted through conjugation with GSH and this mechanism is extremely important for the health status, since exposure to POPs has been associated to diabetes, cardiovascular diseases and many other chronic diseases ( ROS production can occur at several intracellular sites but, for most cells, takes place in the mitochondria and the mitochondrial electron transport chain is the main cellular process of ROS generation in physiological circumstances ( 2 O 2 )
Perform a skin test before the first use to avoid possible allergic reactions
The first enzyme, glutamate cysteine ligase (GCL), joins the amino acids glutamate and cysteine together to form gamma-glutamylcysteine (Glyteine)
Once a healthcare professional has properly trained you, an intramuscular injection is easily administered