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Co to jest Melanotan II (MT-II)

doi: 10.1002/biof.1406 122 WieraGNowakDvan HoveIDziegielPMoonsLMozrzymasJW

Daver N, Basu S, Garcia-Manero G, Cortes JE, Ravandi F, Jabbour EJ, Hendrickson S, Pierce S, Ning J, Konopleva M, Andreeff M , Kornblau SM, Pemmaraju N, Bueso-Ramos CE, Blando J, Lopez JE, Allison J, Kantarjian HM, Sharma P

Adding the 9mg arm suggests the sponsor believes the 8mg to 12mg range contains the optimal therapeutic dose and wants more granular data to identify it precisely

(2015) Biochemical Pharmacology

Future studies involving standardized animal experiments, prospective population-based studies, and clinical trials are required to further clarify their efficacy, safety, and clinical translational potential