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The tradeoff is significant: trial participation involves randomization (you may receive a placebo), strict eligibility criteria, and frequent clinic visits

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Because semaglutide reaches a steady state after several weeks of weekly dosing, finding the right dose and schedule should always be done in partnership with a qualified medical provider

While you may see effective weight loss with any of these medications, a 2024 clinical trial compared tirzepatide versus semaglutide over 72 weeks

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