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All samples were collected with the patients written informed consent

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That does not automatically make it worse, but it does mean the research question is different

[11] If you cannot boil the water, or do not want to lose water by boiling it, bleach is the next best option: [12] Mix in tsp (2.5 mL) of unscented, additive-free bleach for every 5 gallons (19 liters) of water