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Appears to relate to levels of ammonia and the valproic acid metabolite 2-propyl-2-pentenoic acid (rather than valproic acid itself)

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For patients planning pregnancy, semaglutide should be discontinued at least 2 months before a planned pregnancy due to the long half-life, while tirzepatide may persist for approximately 1 month

D.ChakrabartyD.TrivediP