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2024 3 Managed Health Care Executive, Weathering the GLP-1 Storm, Feb
TGF-1: transforming growth factor beta 1
In the STEP clinical trial program evaluating Wegovy for weight management, participants achieved mean weight reductions of 12% to 15% of baseline body weight over 68 weeks, significantly exceeding results seen with lifestyle modification alone
These two studies pinpointed that the effects of cyst(e)ine depletion are not linear, but rather form an intertwined metabolic network to drive ferroptotic cell death
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