Weight loss drug semaglutide may reduce alcohol cravings, heavy drinking and smoking, new study finds Semaglutide, a medication widely used for diabetes and weight loss, may offer another unexpected benefit -- it could help people drink less alcohol
It offers a clinically studied form, clear dosing, and no complicated mixing
Some studies have involved doses of 500 mcg/day up to 1 mg/day
Tirzepatide is a dual GLP-1 and GIP receptor agonist delivered through a once-weekly injection
A history of certain conditions may require extra caution
In addition, GLP-1 increases the activity of protein kinase C (PKC) in islet cells in a dose-dependent manner, promotes pancreatic -cell survival, and inhibits mitochondria-dependent apoptosis by regulating Bcl-2/Bax expression levels (Zhang et al., 2015)