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The p53(3KR) mutant, lacking acetylation due to lysine-to-arginine substitutions at three residues, decreases expression of SLC7A11 without affecting other p53 targets such as CDKN1A/p21 (involved in cell cycle progression) or BAX (involved in apoptosis)

PubMed Central PMCID: PMC2696075

Our bodies absorb Vitamin B12 through the digestive system, so individuals with gut issues, such as Crohns disease or celiac disease, may have trouble absorbing enough Vitamin B12 through their diet alone

doi: 10.1111/ppa.12713 84 Ramrez-TejeroJ

While there have been conflicting reports regarding ROS generation in cells treated with NSAIDs 53 , colon cancer cells reportedly exhibit stronger ROS generation than other cancer cell types 54,55 , which is consistent with the findings of our present study

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