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It corresponds to residues 177 through 191 of its parent sequence, with a tyrosine residue at the N-terminus in place of the phenylalanine found at position 176

Because of its interaction with NNMT-related pathways, the compound has been used in experimental models studying metabolic signalling networks, enzyme inhibition dynamics and cellular regulatory processes

Significant main effects of treatment group (prior to BenjaminiHochberg correction since none were significant after correction, although the necessity of correction for multiple comparisons in exploratory analyses remains unresolved 49 ) were observed for the unclassified group and ten classified genera, namely, Acetatifactor , Akkermansia , Erysipelatoclostridium , [ Eubacterium ] coprostanoligenes group , Family XIII UCG-001 , Lactobacillus , Parasutterella , Ruminiclostridium 6 , Ruminococcaceae UCG-004 , and Ruminococcaceae UCG-009

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Lindenbaum J, Rosenberg IH, Wilson PW, Stabler SP, Allen RH: Prevalence of cobalamin deficiency in the Framingham elderly population