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The extended 2030 hour half-life of IGF-1 LR3 means once-daily dosing maintains elevated IGF-1 receptor occupancy across multiple protein synthesis cycles, unlike native IGF-1s 10-minute half-life that requires frequent re-dosing

Observations in large animal models such as cattle and swine have suggested that IGF-1 LR3 exposure may be associated with sustained cellular turnover

doi: 10.1016/j.ebiom.2018.06.005 Summary Keywords tubular injury, diabetic kidney disease, mechanism, therapy, programmed cell death, stem cell Citation Wang Y, Jin M, Cheng CK and Li Q (2023) Tubular injury in diabetic kidney disease: molecular mechanisms and potential therapeutic perspectives

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Growth performance and starch utilization in common carp (Cyprinus carpio L.) in response to dietary chromium chloride supplementation

This is why sticking to established research protocols is paramount