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They come out on the other end of this journey a healthier, more vibrant version of themselves with a brand new eating strategy theyre already fully acclimated to
No larger study has currently validated the same conclusion
Kim JY, Jeon JH, Choi TH, Kim BJ
Here, we present a comprehensive study in -cells and primary mouse and human islets that demonstrates that, following GLP-1RA stimulation, GLP-1R-positive endosomes associate with the endoplasmic reticulum (ER) membrane contact site (MCS) tether VAPB at ER-mitochondria MCSs (ERMCSs), where active GLP-1R engages with SPHKAP, an A-kinase anchoring protein (AKAP) linked to T2D and adiposity risk in genome-wide association studies (GWAS)