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In addition to the original genotype 1b isolate, called Con1, replicons have now been established for other 1b isolates and for genotypes 1a and 2a, and HCV RNA replication has been achieved in Hela, 293, HepG2 and even mouse hepatoma cell lines 13

Journal of Orthopaedic Research, 2015, 33(7): 1024-1033

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In addition, a substance which has not been approved for human use is likely to be prohibited as well

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Similarly, if you experience constipation, over-the-counter stool softeners and increased hydration are effective