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Topiramate acts primarily by modulating neurotransmitters such as GABA and glutamate, which play significant roles in regulating appetite and reward-driven eating

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Both studies have primary completion dates in September 2025

Lillys triple agonist retatrutide drove substantial improvements in weight, A1C, knee osteoarthritis pain and obstructive sleep apnea, demonstrating its potential to treat obesity and its complications [press release]

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