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To determine if FXR1 influences GPX4 expression by binding to its 3UTR, two luciferase reporters were constructed: G3U-Luci containing the full-length 3UTR of GPX4, and G3U-Luci mut containing the 3UTR of GPX4 with the FXR1 recognition motif mutated (Figure 6H)
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CGMP refers to the Current Good Manufacturing Practice regulations enforced by the FDA
In a study by Burtscher et al
Smolen G, Bender J (2002) Arabidopsis cytochrome P450 cyp83B1 mutations activate the tryptophan biosynthetic pathway
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