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Neuropathy is believed to result from pyridoxine neurotoxicity to dorsal root ganglia when plasma levels are excessively high

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Standard research protocols involve nasal spray administration , which provides direct CNS access

By weeks 3-4, users following a consistent caloric deficit may notice subtle changes: slightly looser-fitting clothing around the midsection, a minor reduction in waist measurement (0.5-1 cm), and potentially 0.5-1 kg of fat loss on top of what diet alone would produce